Description

1-β-Arabinofuranosylthymine 5'-Monophosphate is a nucleotide analog with significant biochemical and pharmaceutical research applications. This compound is valued for its role as a key intermediate and reference standard in the development of antiviral and anticancer therapeutics. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study DNA/RNA metabolism and polymerase activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Prodrug Synthesis: Acts as a precursor for the development of nucleotide prodrugs with enhanced bioavailability.
• Life Science Reagents: Incorporated into specialized kits and reagents for molecular biology and diagnostic applications.

Basic Information

Product Name	1-β-Arabinofuranosylthymine 5'-Monophosphate
CAS No.	21052-26-6
Molecular Formula	C15H21N2O11P
Molecular Weight	436.31 g/mol
Synonyms	1-β-D-Arabinofuranosylthymine 5'-Monophosphate; AraTMP; Thymine Arabinoside Monophosphate; β-Ara-TMP; 5'-TMP-β-D-Arabinofuranoside; 1-(β-D-Arabinofuranosyl)thymine 5'-phosphate; 5'-O-Phosphono-1-β-D-arabinofuranosylthymine
EINECS	Contact for details

Quality Control

Our 1-β-Arabinofuranosylthymine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.