Description

1-[3,4-Dihydro-5-(Hydroxymethyl)-2,4-Dioxopyrimidin-1(2H)-Yl]-1-Deoxy-β-D-Allofuranuronic Acid is a high-purity nucleoside derivative with significant value in advanced pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation nucleoside analogs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP conditions.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-[3,4-Dihydro-5-(Hydroxymethyl)-2,4-Dioxopyrimidin-1(2H)-Yl]-1-Deoxy-β-D-Allofuranuronic Acid
CAS No.	21027-34-9
Molecular Formula	C11H14N2O9
Molecular Weight	318.24 g/mol
Synonyms	5-Hydroxymethyl-2'-deoxyuridine-5'-carboxylic Acid; 5-(Hydroxymethyl)-2'-deoxyuridine-5'-carboxylic Acid; 1-[3,4-Dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-1-deoxy-β-D-allofuranuronic Acid; HMdU-5'-COOH; 5-Hydroxymethyldeoxyuridine-5'-carboxylic Acid; 5-HMdUrd-5'-COOH; β-5-Hydroxymethyl-2'-deoxyuridine-5'-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-[3,4-Dihydro-5-(Hydroxymethyl)-2,4-Dioxopyrimidin-1(2H)-Yl]-1-Deoxy-β-D-Allofuranuronic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.