Description

2β-Methyl-5α-Cholestan-3α-Yl Thiocyanate is a high-purity, synthetic steroidal thiocyanate derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel bioactive molecules and complex natural product analogs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in steroid chemistry, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroidal drugs and hormone analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic agents targeting nuclear receptors.
• Organic Synthesis: Serves as a versatile building block for the total synthesis of complex natural products and specialized steroidal frameworks.
• Biochemical Research: Employed as a reference standard or probe in studies investigating sterol metabolism and membrane biology.
• Fine Chemical Production: An intermediate in the multi-step synthesis of high-value, specialized chemicals for academic and industrial applications.

Basic Information

Product Name	2β-Methyl-5α-Cholestan-3α-Yl Thiocyanate
CAS No.	20997-62-0
Molecular Formula	C₂₉H₄₉NS
Molecular Weight	443.78 g/mol
Synonyms	3α-Thiocyanato-2β-methyl-5α-cholestane; 2β-Methyl-5α-cholestan-3α-yl thiocyanate; 5α-Cholestan-3α-yl thiocyanate, 2β-methyl-; NSC 163044; 2β-Methylcholestanyl thiocyanate; (3α)-2β-Methyl-5α-cholestanyl thiocyanate; Thiocyanic acid, (2β-methyl-5α-cholestan-3α-yl) ester
EINECS	Contact for details

Quality Control

Our 2β-Methyl-5α-Cholestan-3α-Yl Thiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.