Description

2α-Methyl-5α-Cholestan-3α-Ol Acetate is a high-purity sterol derivative, a key intermediate in the synthesis of complex steroid-based compounds. Its defined stereochemistry and consistent quality are critical for research and development in advanced pharmaceutical and fine chemical manufacturing. This compound is essential for scientists and production specialists in the pharmaceutical, biotechnology, and advanced organic synthesis sectors who require reliable building blocks for creating novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related steroid compounds.
• Biochemical Research: Employed in academic and industrial research to study sterol metabolism, receptor interactions, and the development of enzyme inhibitors.
• Fine Chemical Synthesis: Serves as a chiral starting material or intermediate for the production of specialized fine chemicals with specific stereochemical configurations.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	2α-Methyl-5α-Cholestan-3α-Ol Acetate
CAS No.	20997-52-8
Molecular Formula	C₃₀H₅₂O₂
Molecular Weight	444.74 g/mol
Synonyms	3α-Acetoxy-2α-methyl-5α-cholestane; 2α-Methylcholestan-3α-ol acetate; (3α,5α)-3-(Acetyloxy)-2-methylcholestane; 2-Methyl-5α-cholestan-3α-yl acetate; Stigmastane derivative, 2α-methyl-3α-acetoxy-5α-
EINECS	Contact for details

Quality Control

Every batch of 2α-Methyl-5α-Cholestan-3α-Ol Acetate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting compliance with cGMP guidelines for advanced intermediates. A detailed Certificate of Analysis (COA) with batch-specific results from HPLC, NMR, and other relevant analytical techniques is available for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.