Description

14,15β-Epoxy-3β,19-Dihydroxy-5β-Bufa-20,22-Dienolide is a specialized bufadienolide derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and novel therapeutic agents. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise and reliable synthetic precursors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel cardiac glycosides and other bioactive steroid derivatives.
• Biochemical Research: Used as a reference standard or active compound in pharmacological studies targeting Na+/K+-ATPase inhibition and related pathways.
• Fine Chemical Synthesis: Employed in the development of complex molecular architectures for medicinal chemistry and drug discovery programs.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of bufadienolides.

Basic Information

Product Name	14,15β-Epoxy-3β,19-Dihydroxy-5β-Bufa-20,22-Dienolide
CAS No.	20987-26-2
Molecular Formula	C₂₄H₃₂O₅
Molecular Weight	400.51 g/mol
Synonyms	14,15-Epoxy-3,19-dihydroxy-5-bufa-20,22-dienolide; 3,19-Dihydroxy-14,15-epoxy-5-bufa-20,22-dienolide; Bufadienolide derivative; 5β-Bufa-20,22-dienolide, 14,15-epoxy-3,19-dihydroxy-; 14,15β-Epoxy-3β,19-dihydroxy-5β-bufa-20,22-dienolide; 3β,19-Dihydroxy-14β,15β-epoxy-5β-bufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Our 14,15β-Epoxy-3β,19-Dihydroxy-5β-Bufa-20,22-Dienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.