Description

14,15β-Epoxy-3β-Hydroxy-19-Oxo-5β,14β-Bufa-20,22-Dienolide is a specialized bufadienolide derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and fine chemical manufacturers focused on cardiology, oncology, and other life science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and other bioactive molecules.
• Biochemical Research: Used as a reference standard or active compound in studies of Na+/K+-ATPase inhibition and related cellular pathways.
• Medicinal Chemistry: Serves as a core scaffold for the development and structure-activity relationship (SAR) studies of new drug candidates.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological investigations of bufadienolides.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create more complex, target-specific chemical entities.

Basic Information

Product Name	14,15β-Epoxy-3β-Hydroxy-19-Oxo-5β,14β-Bufa-20,22-Dienolide
CAS No.	20987-24-0
Molecular Formula	C24H30O5
Molecular Weight	398.50 g/mol
Synonyms	19-Oxobufalin; 19-Oxo-bufalin; 14,15-Epoxy-3-hydroxy-19-oxo-5,14-bufadienolide; 14β,15β-Epoxy-3β-hydroxy-19-oxo-5β-bufa-20,22-dienolide; 3β,14β,15β-Epoxy-14,15-dihydro-19-oxobufalin; Bufadienolide derivative (19-oxo); 19-Ketobufalin; 14,15β-Epoxy-3β-hydroxy-19-oxo-5β,14β-bufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Our 14,15β-Epoxy-3β-Hydroxy-19-Oxo-5β,14β-Bufa-20,22-Dienolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.