Description

5-Carboxymethyluridine is a modified nucleoside derivative of uridine, featuring a carboxymethyl group at the 5-position of the pyrimidine ring. This specific functionalization makes it a valuable building block and intermediate in the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications in drug discovery, nucleic acid research, and the development of diagnostic tools.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel nucleoside-based therapeutics, including potential antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway research, and investigations into RNA modification and function.
• Oligonucleotide Synthesis: Serves as a modified monomer for introducing specific functional groups into synthetic oligonucleotides, enhancing their properties for research or therapeutic use.
• Diagnostic Probe Development: Can be incorporated into nucleic acid probes to improve stability, specificity, or detection capabilities in diagnostic assays.
• Academic & Industrial R&D: Employed in basic scientific research and applied development projects exploring novel nucleic acid chemistries and applications.

Basic Information

Product Name	5-Carboxymethyluridine
CAS No.	20964-06-1
Molecular Formula	C11H14N2O8
Molecular Weight	302.24 g/mol
Synonyms	5-CMO-uridine; 5-(Carboxymethyl)uridine; Uridine, 5-carboxymethyl-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(carboxymethyl)pyrimidine-2,4(1H,3H)-dione; 5-Carboxymethyl-1-β-D-ribofuranosyluracil; 5-Carboxymethyl-Urd
EINECS	Contact for details

Quality Control

Our 5-Carboxymethyluridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets high-purity research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.