Description

2,3,5,6-Tetrafluorophenyl Isothiocyanate is a specialized fluorinated aromatic building block characterized by its reactive isothiocyanate functional group. This compound is highly valued for its role as a key intermediate in the synthesis of advanced materials and bioactive molecules, where the introduction of fluorine atoms and the isothiocyanate moiety are critical for modulating properties. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel compounds with enhanced stability and performance.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents, particularly for creating thiourea derivatives and other heterocycles.
• Agrochemical Synthesis: Serves as a key precursor for developing novel herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Ligand and Chelator Development: Employed in the preparation of specialized ligands for catalysis and metal ion chelation in industrial and research chemistry.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for creating high-performance fluorinated polymers, coatings, and resins with unique chemical resistance.
• Bioconjugation and Labeling Reagent: Utilized for modifying proteins, peptides, and other biomolecules, facilitating the creation of fluorescent probes or affinity labels.
• Organic Synthesis Building Block: A versatile reagent for constructing complex organic molecules, including heterocyclic compounds and liquid crystals.

Basic Information

Product Name	2,3,5,6-Tetrafluorophenyl Isothiocyanate
CAS No.	20925-31-9
Molecular Formula	C7HF4NS
Molecular Weight	207.15 g/mol
Synonyms	Perfluorophenyl Isothiocyanate; 2,3,5,6-Tetrafluorobenzenecarbonothioic Isocyanate; Pentafluorophenyl Isothiocyanate (common misnomer); 2,3,5,6-Tetrafluorophenyl Mustard Oil; Isothiocyanic Acid, 2,3,5,6-Tetrafluorophenyl Ester; NSC 405124; 2,3,5,6-Tetrafluorophenylcarbimido Thioate
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluorophenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.