Description

2,3,5,6-Tetrafluoro-4-(Trifluoromethyl)Benzyl Alcohol is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring a benzyl alcohol group on a perfluorinated aromatic ring, makes it a critical intermediate for introducing fluorine-rich motifs into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including protease inhibitors, kinase inhibitors, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), enhancing dielectric anisotropy and thermal stability.
• Advanced Polymer Chemistry: Building block for synthesizing specialty fluorinated polymers and coatings with exceptional chemical resistance, low surface energy, and thermal properties.
• Organic Electronics: Intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-(Trifluoromethyl)Benzyl Alcohol
CAS No.	20867-94-1
Molecular Formula	C8H3F7O
Molecular Weight	248.10 g/mol
Synonyms	α,2,3,5,6-Pentafluoro-4-(trifluoromethyl)benzyl Alcohol; (2,3,5,6-Tetrafluoro-4-trifluoromethylphenyl)methanol; 4-(Trifluoromethyl)-2,3,5,6-tetrafluorobenzyl Alcohol; 2,3,5,6-Tetrafluoro-α,α,α,4-tetrakis(trifluoromethyl)benzyl Alcohol (incorrect but sometimes listed); Perfluorinated Benzyl Alcohol Derivative; TFBA Alcohol Derivative
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoro-4-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.