Description

17-o-Acetyl-3-o-Methyl-6-Oxo 17β-Estradiol is a high-purity, synthetically modified steroid derivative of estradiol. This compound is a critical pharmaceutical intermediate and a valuable reference standard for analytical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of novel steroid-based therapeutics and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of advanced steroid-based drugs and hormonal therapies.
• Reference Standard: Used for method development, calibration, and quality control in analytical laboratories (HPLC, GC-MS, NMR).
• Biochemical Research: Serves as a precursor or model compound in studies of steroid metabolism, receptor binding, and enzyme inhibition.
• Academic & R&D: Employed in university and institutional research for exploring new synthetic pathways and biological activities of estradiol derivatives.

Basic Information

Product Name	17-o-Acetyl-3-o-Methyl-6-Oxo 17β-Estradiol
CAS No.	20823-31-8
Molecular Formula	C21H26O4
Molecular Weight	342.43 g/mol
Synonyms	17β-Estradiol 17-acetate 3-methyl ether 6-one; 3-Methoxy-6-oxoestra-1,3,5(10)-trien-17β-yl acetate; 6-Oxoestradiol 3-methyl ether 17-acetate; 17β-Acetoxy-3-methoxyestra-1,3,5(10)-trien-6-one; 3-Methoxy-6-oxo-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol acetate; Estra-1,3,5(10)-triene-3,17β-diol, 17-acetate, 3-methyl ether, 6-oxo-; 20823-31-8
EINECS	Contact for details

Quality Control

Our 17-o-Acetyl-3-o-Methyl-6-Oxo 17β-Estradiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic methods (IR, NMR) for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.