Description

Bis(3'-5')Cyclic(Uridylyl-Adenosine Monophosphate) CAS NO 20787-33-1 is a specialized cyclic dinucleotide compound, a key structural motif in cellular signaling pathways. This high-purity biochemical is critical for research and development in advanced life sciences, particularly in the study of second messenger systems and innate immunity. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on immunology, virology, and novel therapeutic discovery.

Application

• Biochemical Research: Essential tool compound for studying the cGAS-STING signaling pathway and its role in innate immune response.
• Pharmaceutical Development: Serves as a reference standard and potential intermediate in the development of STING pathway agonists and immunotherapies.
• Vaccine Adjuvant Research: Investigated for its potential as a potent adjuvant to enhance vaccine efficacy by modulating immune recognition.
• Cell Signaling Studies: Used in vitro and in vivo to activate interferon production and study downstream inflammatory responses.
• Diagnostic Reagent Manufacturing: A key component in the production of high-sensitivity assay kits for detecting immune pathway activity.
• Academic & Institutional Research: Fundamental reagent for groundbreaking studies in molecular biology, virology, and cancer immunology.

Basic Information

Product Name	Bis(3'-5')Cyclic(Uridylyl-Adenosine Monophosphate)
CAS No.	20787-33-1
Molecular Formula	C20H22N10O14P2
Molecular Weight	688.39 g/mol
Synonyms	c[G(2',5')pA(3',5')p]; 2',3'-cGAMP; Cyclic [G(2',5')pA(3',5')p]; Cyclic GMP-AMP; cGAMP; 3'3'-cGAMP; Cyclic di-GMP-AMP; Mixed-linkage cyclic dinucleotide
EINECS	Contact for details

Quality Control

Our Bis(3'-5')Cyclic(Uridylyl-Adenosine Monophosphate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the exacting standards required for critical research applications. Certificates of Analysis (COA) with full chromatographic data are provided to guarantee traceability, consistency, and reliability for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.