Description

2-Bromoisobutyryl Bromide is a highly reactive bifunctional reagent, primarily serving as a key initiator in controlled radical polymerization techniques. Its precise molecular structure makes it indispensable for the synthesis of well-defined polymers with specific architectures and end-group functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, advanced materials, and polymer science industries who require high-purity building blocks for creating block copolymers, polymer brushes, and functionalized surfaces.

Application

• ATRP Initiator: The primary application is as a fundamental initiator for Atom Transfer Radical Polymerization (ATRP), enabling the synthesis of polymers with controlled molecular weight and low polydispersity.
• Surface Functionalization: Used to create self-assembled monolayers (SAMs) or to graft polymer brushes from surfaces (e.g., silicon, gold, polymers) for modifying surface properties like wettability, adhesion, or biocompatibility.
• Macroinitiator Synthesis: Employed to introduce bromoisobutyrate groups onto polymers, peptides, or other macromolecules, converting them into macroinitiators for the growth of polymer blocks.
• Pharmaceutical Intermediates: Serves as a versatile building block in organic synthesis for introducing the bromoisobutyryl moiety, which is valuable in medicinal chemistry and the synthesis of complex bioactive molecules.
• Polymer Brush Fabrication: Critical for "grafting-from" strategies to create dense polymer brushes on nanoparticles or flat substrates for applications in drug delivery, lubricants, and anti-fouling coatings.
• Block Copolymer Production: Facilitates the precise synthesis of di-block, tri-block, and star-shaped copolymers with tailored properties for use in nanotechnology, elastomers, and compatibilizers.

Basic Information

Product Name	2-Bromoisobutyryl Bromide
CAS No.	20769-85-1
Molecular Formula	C4H6Br2O
Molecular Weight	229.90 g/mol
Synonyms	2-Bromo-2-methylpropanoyl Bromide; α-Bromoisobutyryl Bromide; BIBB; 2-Bromoisobutyric Acid Bromide; 2-Bromo-2-methylpropionyl Bromide; Isobutyryl Bromide, 2-bromo-; (Bromocarbonyl)-2-bromo-2-methylpropane
EINECS	244-052-0

Quality Control

Every batch of our 2-Bromoisobutyryl Bromide is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, which is critical for reproducible polymerization results and synthetic outcomes. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive (hygroscopic) and corrosive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Color (APHA)	≤ 50
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.