Description

2,5'-Anhydro-Uridine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. Its unique anhydro bridge structure makes it a valuable synthetic intermediate and a key building block for exploring novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of modified RNA molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Probe Development: Serves as a building block for creating fluorescent or affinity-labeled nucleoside probes for molecular biology.
• Antiviral Research: Investigated for its potential activity or as a scaffold in the development of compounds targeting viral polymerases.
• Modified Oligonucleotide Synthesis: Incorporated into oligonucleotides to study structure-activity relationships and RNA function.
• Chemical Biology Tool: Employed to study cellular processes involving uridine metabolism and incorporation.

Basic Information

Item	Details
Product Name	2,5'-Anhydro-Uridine
CAS No.	20701-12-6
Molecular Formula	C9H10N2O5
Molecular Weight	226.19 g/mol
Synonyms	2,5'-Anhydro-1-β-D-ribofuranosyluracil; 2,2'-Anhydro-1-β-D-ribofuranosyluracil; 2,5'-Cyclouridine; Uridine, 2,5'-anhydro-; 1-(2,5-Anhydro-β-D-ribofuranosyl)uracil; 2,5'-O-Cyclouridine; NSC 143491; 2,2'-O-Cyclouridine (common misnomer)
EINECS	Contact for details

Quality Control

Our 2,5'-Anhydro-Uridine is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.