Description

α-D-Glucopyranosylphenyl Isothiocyanate is a specialized glycosyl isothiocyanate derivative that serves as a critical building block in synthetic carbohydrate chemistry. Its unique structure, featuring a reactive isothiocyanate group linked to a glucopyranosyl moiety, enables the synthesis of complex glycoconjugates and thiourea-linked neoglycoproteins. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing targeted therapeutics, diagnostic probes, and novel materials based on carbohydrate recognition.

Application

• Glycoconjugate Synthesis: A key reagent for the chemoselective preparation of thiourea-bridged glycoconjugates, glycodendrimers, and carbohydrate arrays.
• Pharmaceutical Research: Used in the development of carbohydrate-based drug candidates, prodrugs, and targeted delivery systems that exploit lectin-mediated recognition.
• Diagnostic Probe Development: Facilitates the labeling of proteins, antibodies, or surfaces with carbohydrate epitopes for biosensor, microarray, and immunoassay applications.
• Biomaterial Functionalization: Enables the surface modification of polymers, nanoparticles, and chips with bioactive sugar motifs to study cell adhesion and signaling.
• Chemical Biology Tools: Employed in the synthesis of activity-based probes (ABPs) and affinity labels for studying glycosidases and carbohydrate-binding proteins.
• Standards and Reference Materials: Serves as a high-purity analytical standard for quality control and method development in carbohydrate analysis.

Basic Information

Product Name	α-D-Glucopyranosylphenyl Isothiocyanate
CAS No.	20581-45-7
Molecular Formula	C₁₃H₁₅NO₆S
Molecular Weight	313.33 g/mol
Synonyms	Phenyl 1-Thioisocyanato-1-deoxy-α-D-glucopyranoside; 1-Deoxy-1-isothiocyanatophenyl-α-D-glucopyranoside; α-D-Glucopyranosyl phenyl isothiocyanate; Phenyl α-D-glucopyranosyl isothiocyanate; Glucosylphenyl isothiocyanate; α-Glucosyl phenyl isothiocyanate; 20581-45-7; NSC 401016
EINECS	Contact for details

Quality Control

Our α-D-Glucopyranosylphenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for moisture and residual solvents. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.