Description

β-D-Glucopyranosylphenyl Isothiocyanate is a specialized glycosyl isothiocyanate derivative, a key building block in synthetic carbohydrate chemistry. Its primary value lies in its reactive isothiocyanate group, which enables efficient conjugation to amines and other nucleophiles for the synthesis of glycoconjugates and labeled probes. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors developing targeted therapeutics, novel biosensors, and advanced biochemical tools.

Application

• Glycoconjugate Synthesis: A critical reagent for covalently linking carbohydrate moieties to proteins, peptides, or other biomolecules to create neoglycoconjugates for immunological and drug delivery studies.
• Affinity Labeling Probes: Used in the development of activity-based probes (ABPs) for studying carbohydrate-processing enzymes like glycosidases and glycosyltransferases.
• Pharmaceutical Intermediate: Serves as a key synthetic intermediate in the research and development of glycosylated drug candidates and targeted therapies.
• Diagnostic Reagent Manufacturing: Employed in the production of labeled substrates and detection reagents for enzymatic assays and diagnostic kits.
• Biomaterial Functionalization: Facilitates the surface modification of polymers, nanoparticles, and chips with sugar epitopes for biosensing and cell culture applications.
• Chemical Biology Research: A versatile tool for chemoselective ligation in studying carbohydrate-protein interactions and cell surface engineering.

Basic Information

Product Name	β-D-Glucopyranosylphenyl Isothiocyanate
CAS No.	20581-41-3
Molecular Formula	C₁₃H₁₅NO₆S
Molecular Weight	313.33 g/mol
Synonyms	Phenyl 1-Thio-β-D-glucopyranoside Isothiocyanate; Phenyl β-D-Glucopyranosyl Isothiocyanate; 1-Isothiocyanato-1-phenylthio-β-D-glucopyranose; β-D-Glucopyranosyl Phenyl Isothiocyanate; Glucosylphenyl Isothiocyanate; Phenyl Thioglucoside Isothiocyanate; (Phenylthio)glucose Isothiocyanate
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranosylphenyl Isothiocyanate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.