Description

2-Bromoisobutyrylchloride is a versatile and highly reactive organic compound, primarily used as a key initiator in atom transfer radical polymerization (ATRP). Its value lies in its ability to precisely control polymer architecture, enabling the synthesis of polymers with specific molecular weights and low polydispersity. This makes it an essential building block for researchers and manufacturers in the polymer, pharmaceutical, and advanced materials industries seeking to develop novel polymeric structures.

Application

• ATRP Initiator: The primary application is as a crucial initiator for Atom Transfer Radical Polymerization (ATRP), a controlled/"living" radical polymerization technique.
• Functional Polymer Synthesis: Enables the creation of block copolymers, star polymers, graft copolymers, and other polymers with complex, well-defined architectures.
• Surface Modification: Used to functionalize surfaces (e.g., silicon, gold, polymers) by introducing polymer brushes for applications in biomaterials, coatings, and sensors.
• Pharmaceutical Intermediates: Serves as a reactive intermediate in the synthesis of more complex organic molecules and active pharmaceutical ingredients (APIs).
• Macromolecular Engineering: Facilitates research and production in macromolecular engineering for tailored material properties like adhesion, biocompatibility, or mechanical strength.
• Bioconjugation: Employed in modifying biomolecules (e.g., proteins, peptides) by attaching synthetic polymer chains to alter their solubility, stability, or functionality.

Basic Information

Item	Details
Product Name	2-Bromoisobutyrylchloride
CAS No.	20469-89-0
Molecular Formula	C4H6BrClO
Molecular Weight	185.45 g/mol
Synonyms	2-Bromo-2-methylpropanoyl chloride; α-Bromoisobutyryl chloride; 2-Bromoisobutyric acid chloride; 2-Bromo-2-methylpropionyl chloride; BIB-Cl; 2-Bromopropanoyl chloride, 2-methyl-; (Bromomethyl)ethyl ketone chloride
EINECS	243-856-3

Quality Control

Our 2-Bromoisobutyrylchloride is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive acid chloride nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from moisture, strong bases, and oxidizing agents. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.