Description

3β,2α-[[(2S,3S,4R,5S,6R)-Tetrahydro-3,4,5-Trihydroxy-6-Methyl-2H-Pyran-2,3-Diyl]Bisoxy]-14-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is a high-purity, complex cardenolide glycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel cardiac glycosides and other bioactive steroidal molecules. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents or analytical methods.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control of active pharmaceutical ingredients (APIs) and finished drug products.
• Biochemical Research: Serves as a key intermediate or tool compound in studying the structure-activity relationships (SAR) of cardenolides and their interaction with biological targets like Na+/K+-ATPase.
• Lead Compound Development: Acts as a sophisticated scaffold for the semi-synthesis and structural modification of novel candidates with potential cardiotonic or anticancer activity.
• Process Chemistry: Employed in the development and optimization of synthetic routes for complex steroidal natural products and their analogs.
• Academic Research: Utilized in university and institutional labs for pharmacological studies, metabolic pathway investigation, and teaching advanced organic chemistry.

Basic Information

Item	Details
Product Name	3β,2α-[[(2S,3S,4R,5S,6R)-Tetrahydro-3,4,5-Trihydroxy-6-Methyl-2H-Pyran-2,3-Diyl]Bisoxy]-14-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide
CAS No.	20304-49-8
Molecular Formula	C29H42O11
Molecular Weight	566.64 g/mol
Synonyms	19-Oxocymarin; 19-Oxocymarol; 3β,2α-[[(2S,3S,4R,5S,6R)-Tetrahydro-3,4,5-trihydroxy-6-methyl-2H-pyran-2,3-diyl]bisoxy]-14-hydroxy-19-oxo-5α-card-20(22)-enolide; 19-Oxo-α-L-cymarosyl-(1→4)-β-D-digitoxosyl oleandrin genin; A derivative of Cymarin
EINECS	Contact for details

Quality Control

Our 3β,2α-[[(2S,3S,4R,5S,6R)-Tetrahydro-3,4,5-Trihydroxy-6-Methyl-2H-Pyran-2,3-Diyl]Bisoxy]-14-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are provided and can be tailored to meet client-specific monograph requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.