Description

3β-(α-L-Rhamnopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is a specialized cardiac glycoside derivative, a compound of significant interest in advanced pharmaceutical research and development. Its complex steroidal structure, featuring a rhamnose sugar moiety, is key to its biological activity and makes it a valuable reference standard and synthetic intermediate. This high-purity compound is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutic agents, particularly for cardiovascular applications. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for critical research.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in the production and research of cardiac glycosides.
• Biochemical Research: Serves as a crucial tool in pharmacological studies to investigate the mechanism of action of bufadienolide compounds on ion channels and cardiac muscle.
• Drug Discovery Intermediate: Acts as a key synthetic building block or precursor for the development of new therapeutic molecules targeting heart failure and arrhythmias.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of steroidal glycosides.
• Analytical Method Development: Employed to develop and calibrate advanced analytical techniques such as HPLC, LC-MS, and NMR for the detection and quantification of similar compounds.

Basic Information

Product Name	3β-(α-L-Rhamnopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide
CAS No.	20300-44-1
Molecular Formula	C30H42O9
Molecular Weight	546.65 g/mol
Synonyms	19-Oxobufalin 3-rhamnoside; Bufalin 3-O-α-L-rhamnopyranoside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-bufa-20,22-dienolide; 5β-Bufa-20,22-dienolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-; 19-Oxobufalin 3-O-α-L-rhamnoside; Scillarenin rhamnoside (related class); Bufadienolide rhamnoside
EINECS	Contact for details

Quality Control

Every batch of 3β-(α-L-Rhamnopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing all critical parameters are provided to guarantee traceability and suitability for your research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere. Keep the container sealed to protect this moisture-sensitive compound from humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.