Description

(20S)-19-Hydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid Methyl Ester CAS NO 20248-19-5 is a high-purity, synthetically derived steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on endocrinology, oncology, and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel corticosteroid and progestin derivatives for therapeutic applications.
• Steroid Research: Used as a standard or starting material in academic and industrial laboratories studying steroid hormone biosynthesis, metabolism, and receptor interactions.
• API Development: Employed in the research and process development of new steroid-based Active Pharmaceutical Ingredients (APIs) targeting hormonal disorders and inflammatory conditions.
• Reference Standard: Serves as a high-purity analytical reference standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic chemistry research for exploring new synthetic pathways and creating structurally modified steroid analogs with potential biological activity.

Basic Information

Product Name	(20S)-19-Hydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid Methyl Ester
CAS No.	20248-19-5
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	19-Hydroxy-3-oxopregn-4-ene-20-carboxylic acid methyl ester, (20S)-form; Methyl (20S)-19-hydroxy-3-oxopregn-4-ene-20-carboxylate; 19-Hydroxy-3-oxopregn-4-en-20-carboxylic acid methyl ester; Pregn-4-ene-20-carboxylic acid, 19-hydroxy-3-oxo-, methyl ester, (20S)-; 19-Hydroxy-3-oxopregn-4-en-20-oic acid methyl ester; Steroid intermediate 20248-19-5
EINECS	Contact for details

Quality Control

Our (20S)-19-Hydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.