Description

20-Carboxy-1,4-Pregnadien-3-One is a high-purity steroid derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its specific molecular framework, which serves as a crucial building block in the synthesis of more complex bioactive molecules. It is primarily required by research institutions and pharmaceutical development companies engaged in the production of steroid-based APIs, novel drug candidates, and advanced fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs) and investigational new drugs.
• Research & Development: Used in academic and industrial R&D laboratories for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex, high-value organic molecules with specific stereochemistry.
• Process Chemistry: Employed in scaling up synthetic routes during process development and optimization for commercial manufacturing.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	20-Carboxy-1,4-Pregnadien-3-One
CAS No.	20248-18-4
Molecular Formula	C22H28O3
Molecular Weight	340.46 g/mol
Synonyms	20-Carboxy-1,4-pregnadiene-3-one; 3-Oxo-1,4-pregnadiene-20-carboxylic Acid; 1,4-Pregnadiene-3-one-20-carboxylic Acid; Pregna-1,4-diene-3-one-20-carboxylic Acid; 20-Carboxypregna-1,4-dien-3-one; 20-Carboxy-δ1,4-pregnadien-3-one; 20-Carboxy-1,4-pregnadien-3-one (CAS 20248-18-4)
EINECS	Contact for details

Quality Control

Our 20-Carboxy-1,4-Pregnadien-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.