Description

3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-4,20(22)-Dienolide is a high-purity, specialized cardiac glycoside derivative with a complex steroidal structure. This compound is of significant interest for pharmaceutical research and development, particularly in the study of cardiovascular therapeutics and natural product chemistry. It serves as a critical intermediate or reference standard for scientists in medicinal chemistry, pharmacology, and analytical laboratories.

Application

• Pharmaceutical Research & Development: Acts as a key intermediate or building block in the synthesis of novel cardiac glycoside analogs for potential therapeutic applications.
• Reference Standard for Analytical Testing: Used as a certified reference material (CRM) in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the biological activity of cardenolide derivatives.
• Biochemical Research: Utilized as a tool compound in in-vitro assays to investigate interactions with biological targets such as Na+/K+-ATPase.
• Natural Product Isolation & Synthesis: Serves as a benchmark compound in the isolation, purification, and total synthesis of complex natural products.

Basic Information

Product Name	3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-4,20(22)-Dienolide
CAS No.	20248-01-5
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	14-Hydroxy-3β-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]card-4,20(22)-dienolide; 3β-[(6-Deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-14-hydroxycarda-4,20(22)-dienolide; Desglucouzarin; Uzarigenin 3-O-α-L-oleandropyranoside; Oleandrin aglycone derivative; Card-4,20(22)-dienolide, 14-hydroxy-3-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-, (3β)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-4,20(22)-Dienolide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.