Description

9-[(3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-7-Methyl-3H-Purin-9-Ium-6-One is a high-purity nucleoside derivative, also known as 7-Methylguanosine, which serves as a critical building block and reference standard in biochemical research. Its primary value lies in its role as a modified nucleoside for studying RNA structure, function, and epigenetic modifications. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production, where precise chemical tools are required.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving RNA methyltransferases and other RNA-modifying enzymes.
• Diagnostic Reagent Manufacturing: Incorporated into kits and assays for the detection and quantification of RNA modifications or specific enzymatic activities.
• Life Science Tools: Serves as a critical component in the development of probes and tools for studying gene expression and RNA biology.
• Academic Research: Fundamental research into the mechanisms of RNA methylation (epitranscriptomics) and its impact on cellular processes.

Basic Information

Product Name	9-[(3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-7-Methyl-3H-Purin-9-Ium-6-One
CAS No.	20245-33-4
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	7-Methylguanosine; N7-Methylguanosine; 7-Methyl-Guanosine; 7-MeG; 9-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-3H-purin-9-ium-6-olate; 7-Methylguanosine riboside; 1-Methylguanosine (obsolete); Guanosine, 7-methyl-
EINECS	Contact for details

Quality Control

Our 9-[(3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-7-Methyl-3H-Purin-9-Ium-6-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.