Description

7-Methylguanosine is a modified nucleoside where a methyl group is attached to the N7 position of the guanine base. This specific modification is of significant interest in biochemical research, particularly in the study of RNA structure, function, and epigenetic regulation. It serves as a critical reference standard and building block for researchers and manufacturers in the life sciences sector, enabling advancements in nucleic acid chemistry and molecular biology.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the identification and quantification of RNA modifications in analytical studies.
• Nucleic Acid Chemistry: Acts as a key precursor or intermediate in the chemical synthesis of modified oligonucleotides for structural and functional studies.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the activity and specificity of methyltransferases and other RNA-modifying enzymes.
• Epigenetics & Transcriptomics: Essential for research into the role of RNA methylation in gene expression regulation and cellular processes.
• Pharmaceutical Development: Potential use in the development of diagnostic tools or therapeutic agents targeting RNA modification pathways.

Basic Information

Product Name	7-Methylguanosine
CAS No.	20244-86-4
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	N7-Methylguanosine; 7-Methylguanosine; 7-MeG; Guanosine, 7-methyl-; 1-(β-D-Ribofuranosyl)-7-methylguanine; 7-Methyl-Guanosine; 2-Amino-7-methyl-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one
EINECS	Contact for details

Quality Control

Our 7-Methylguanosine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.