Description

7α,12α-Dihydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid is a high-purity steroid derivative and a key synthetic intermediate in the pharmaceutical industry. Its defined stereochemistry and functional groups make it a critical building block for the synthesis of complex therapeutic agents, particularly corticosteroids and other bioactive steroids. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers requiring a reliable source of high-quality steroid intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent corticosteroid drugs and other steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-based therapeutic compounds.
• Biochemical Research: Serves as a reference standard or substrate in studies investigating steroid metabolism, enzyme activity, and receptor binding.
• Fine Chemical Synthesis: Employed as a specialized building block for the custom synthesis of complex, high-value steroid molecules for various applications.

Basic Information

Product Name	7α,12α-Dihydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid
CAS No.	20169-24-8
Molecular Formula	C22H30O5
Molecular Weight	374.47 g/mol
Synonyms	7α,12α-Dihydroxy-3-oxopregn-4-ene-20-carboxylic acid; 3-Oxo-7α,12α-dihydroxypregn-4-ene-20-carboxylic acid; Pregn-4-ene-20-carboxylic acid, 7,12-dihydroxy-3-oxo-, (7α,12α)-; 7α,12α-Dihydroxy-3-oxochol-4-en-24-oic Acid (Steroid numbering); 20-Carboxy-7α,12α-dihydroxy-3-oxopregn-4-ene
EINECS	Contact for details

Quality Control

Our 7α,12α-Dihydroxy-3-Oxopregn-4-Ene-20-Carboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.