Description

(4-Nitrophenoxy)Acetyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in the synthesis of more complex molecules. Its value lies in the reactive acid chloride group and the nitro-substituted aromatic ring, which facilitate further chemical transformations under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a phenoxyacetyl moiety.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators where the nitro group serves as a handle for further functionalization.
• Peptide Chemistry: Acts as an acylating agent for the introduction of the (4-nitrophenoxy)acetyl protecting group or label onto amino acids and peptides.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with specific optical or electronic properties.
• Dye & Pigment Manufacturing: Employed in the synthesis of azo dyes and other complex colorants where it contributes to chromophore structure.
• Research & Development: A valuable reagent in organic synthesis laboratories for constructing complex molecular architectures and exploring new chemical reactions.

Basic Information

Product Name	(4-Nitrophenoxy)Acetyl Chloride
CAS No.	20142-88-5
Molecular Formula	C8H6ClNO4
Molecular Weight	215.59 g/mol
Synonyms	4-Nitrophenoxyacetyl chloride; 2-(4-Nitrophenoxy)acetyl chloride; p-Nitrophenoxyacetyl chloride; Acetyl chloride, (p-nitrophenoxy)-; (p-Nitrophenoxy)acetyl chloride; 4-Nitro-phenoxyacetyl chloride; 2-(4-Nitrophenoxy)ethanoyl chloride
EINECS	Contact for details

Quality Control

Our (4-Nitrophenoxy)Acetyl Chloride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.