Description

Makisterone A is a naturally occurring phytoecdysteroid, a plant-derived analog of insect molting hormones. This compound is of significant interest in biochemical research for its role in insect growth regulation and its potential bioactivity in mammalian systems. It serves as a critical reference standard and intermediate for researchers and developers in the agrochemical, pharmaceutical, and life science sectors. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Agrochemical Research: As a key reference standard in the study of insect growth regulators (IGRs) and the development of novel, environmentally friendly pesticides.
• Pharmaceutical R&D: Investigation of potential anabolic, adaptogenic, or other pharmacological activities in mammalian cell lines and model organisms.
• Biochemical Studies: Used in receptor binding assays and metabolic pathway analysis to understand ecdysteroid signaling and its cross-kingdom effects.
• Plant Physiology Research: Study of the role of phytoecdysteroids in plant defense mechanisms and their ecological interactions with insects.
• Reference Standard Manufacturing: Serves as a high-purity primary standard for the calibration of analytical instruments and quality control of related products.
• Nutritional Supplement R&D: Exploration as a potential bioactive ingredient, requiring extensive safety and efficacy profiling.

Basic Information

Product Name	Makisterone A
CAS No.	20137-14-8
Molecular Formula	C₂₉H₄₈O₈
Molecular Weight	524.7 g/mol
Synonyms	20-Hydroxyecdysone 20,22-acetonide; 2β,3β,14α,20R,22R,25-Hexahydroxy-5β-cholest-7-en-6-one 20,22-acetonide; 20,22-O-(Isopropylidene)ecdysone; Makisteron A; 20-Hydroxyecdysone 20,22-O-isopropylidene acetal
EINECS	Contact for details

Quality Control

Every batch of Makisterone A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity assays and spectroscopic identification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use within the primary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.