Description

Nicotinoyl Chloride Hydrochloride is a key reactive intermediate in organic synthesis, valued for its role in introducing the nicotinoyl moiety. This compound is essential for the production of various pharmaceuticals and fine chemicals, particularly those targeting metabolic and neurological pathways. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of nicotinic acid derivatives, vitamin B3 analogs, and various active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of certain herbicides and plant growth regulators that incorporate the pyridine structure.
• Biochemical Research: Serves as a reagent for modifying proteins, peptides, and other biomolecules in proteomics and metabolic studies.
• Fine Chemical Production: Employed in the manufacture of dyes, photoinitiators, and other specialty chemicals requiring the nicotinoyl functional group.
• Ligand and Catalyst Preparation: Acts as a precursor for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	Nicotinoyl Chloride Hydrochloride
CAS No.	20060-53-1
Molecular Formula	C6H5Cl2NO
Molecular Weight	178.02 g/mol
Synonyms	3-Pyridinecarbonyl chloride hydrochloride; Nicotinic acid chloride hydrochloride; Nicotinyl chloride hydrochloride; Pyridine-3-carbonyl chloride hydrochloride; 3-Carbamoylpyridine hydrochloride chloride; Nicotinoyl chloride HCl; 3-Picolinoyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our Nicotinoyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	~155-160 °C (dec.)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.