Description

Cimetidine CAS NO 2984-61-4 is a histamine H₂-receptor antagonist widely recognized for its therapeutic applications. This compound is critical for the pharmaceutical industry, serving as a key active pharmaceutical ingredient (API) in the formulation of medications. It is primarily utilized by manufacturers of finished dosage forms, research institutions, and chemical distributors serving the global healthcare sector.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter medications for gastric acid reduction.
• Gastrointestinal Therapeutics: Formulation of drugs for treating peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome.
• Research & Development: A standard reference compound in pharmacological studies of H₂-receptor mechanisms and drug discovery.
• Veterinary Medicine: Used in veterinary pharmaceuticals for managing gastric ulcers in animals.
• Chemical Intermediate: Serves as a synthetic intermediate for further chemical modifications in specialized organic synthesis.
• Academic & Clinical Studies: Employed in university and hospital laboratories for biochemical and clinical research.

Basic Information

Product Name	Cimetidine
CAS No.	2984-61-4
Molecular Formula	C10H16N6S
Molecular Weight	252.34 g/mol
Synonyms	N"-Cyano-N-methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine; SKF-92334; Tagamet; Cimetidin; Cimetidina; Cimetidinum; Cimetidihydrochloride
EINECS	221-041-8

Quality Control

Our Cimetidine is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including compliance with relevant pharmacopeial monographs. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.