Description

3,12-Dioxo-5-β-Cholan-24-Oic Acid is a high-purity steroidal bile acid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its defined structure is essential for the development of steroid-based therapeutics and as a reference standard in analytical chemistry. This compound is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies and enzyme research.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Fine Chemical Synthesis: Intermediate for producing specialized cholanic acid derivatives and other complex organic molecules.

Basic Information

Product Name	3,12-Dioxo-5-β-Cholan-24-Oic Acid
CAS No.	2958-05-6
Molecular Formula	C24H34O5
Molecular Weight	402.53 g/mol
Synonyms	3,12-Diketolithocholic Acid; 3,12-Dioxolithocholic Acid; 5β-Cholan-24-oic acid, 3,12-dioxo-; Lithocholic Acid 3,12-Dione; 3,12-Diketo-5β-cholan-24-oic Acid; 3α-Hydroxy-12-oxo-5β-cholan-24-oic Acid (tautomer); 12-Oxo-3-dehydrocholic Acid
EINECS	220-974-2

Quality Control

Our 3,12-Dioxo-5-β-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets stringent specifications for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.