Description

Adenine, 9-α-D-Xylofuranosyl- CAS NO 2946-52-3 is a nucleoside analog of adenine, where the adenine base is linked to an α-D-xylofuranosyl sugar moiety. This specific structural configuration makes it a valuable intermediate and reference standard in the research and synthesis of modified nucleosides and nucleotides. It is primarily utilized by research institutions and pharmaceutical development companies engaged in antiviral, anticancer, and metabolic pathway studies. The compound's role is critical for exploring structure-activity relationships in medicinal chemistry.

Application

• Pharmaceutical Research Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based drug candidates for antiviral and anticancer therapies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related biological pathways.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development and quality control of related compounds.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, glycoscience, and medicinal chemistry.
• Process Development: Acts as a starting material or intermediate in the scale-up and process optimization for the manufacture of specialized nucleosides.

Basic Information

Product Name	Adenine, 9-α-D-Xylofuranosyl-
CAS No.	2946-52-3
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	9-α-D-Xylofuranosyladenine; Adenine, 9-α-D-xylofuranosyl-; 9-(α-D-Xylofuranosyl)adenine; 9-α-D-Xylosyladenine; α-D-Xylofuranosyladenine; NSC 403169; 6-Amino-9-α-D-xylofuranosyl-9H-purine
EINECS	220-952-5

Quality Control

Every batch of Adenine, 9-α-D-Xylofuranosyl- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development applications. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and residual solvent analysis is supplied with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.