Description

9-(6'-Deoxy-β-D-Allofuranosyl)-6-Thiopurine CAS NO 2946-43-2 is a specialized nucleoside analog, a key building block in medicinal chemistry and biochemical research. This compound is valued for its role as a precursor or intermediate in the synthesis of modified nucleosides and potential therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in antiviral, anticancer, or metabolic pathway research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based drugs targeting viral infections and specific cancers.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand purine metabolism and nucleoside processing pathways.
• Antiviral Agent Development: Investigated for its potential incorporation into oligonucleotide analogs designed to disrupt viral replication.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9-(6'-Deoxy-β-D-Allofuranosyl)-6-Thiopurine
CAS No.	2946-43-2
Molecular Formula	C₁₀H₁₂N₄O₄S
Molecular Weight	284.29 g/mol
Synonyms	6-Thio-9-(6-deoxy-β-D-allofuranosyl)purine; 9-(6-Deoxy-β-D-allofuranosyl)-6-mercaptopurine; 6-Thiopurine, 9-(6-deoxy-β-D-allofuranosyl)-; 6-Thiopurine riboside analog (6-deoxy-allofuranosyl); NSC 143491; 2946-43-2; 9-(6-Deoxy-β-D-allofuranosyl)-6-thiopurine
EINECS	Contact for details

Quality Control

Our 9-(6'-Deoxy-β-D-Allofuranosyl)-6-Thiopurine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.