Description

1-(4-Fluoro-Phenyl)-2-Methyl-Propan-2-Ol is a versatile fluorinated tertiary alcohol intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of pharmaceuticals and agrochemicals, where the fluorine atom and tertiary alcohol moiety are crucial for modulating biological activity and physicochemical properties. Industries that require high-purity, specialized intermediates for research and production, such as pharmaceutical R&D, agrochemical manufacturing, and fine chemical synthesis, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine substituent enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and additives for specialty polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and process chemistry optimization in laboratory-scale and pilot-scale operations.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-2-Methyl-Propan-2-Ol
CAS No.	2928-17-8
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	1-(4-Fluorophenyl)-2-methylpropan-2-ol; 2-(4-Fluorophenyl)-2-methyl-1-propanol; p-Fluoro-α,α-dimethylbenzyl alcohol; 4-Fluoro-α,α-dimethylbenzyl alcohol; 1-(p-Fluorophenyl)-2-methyl-2-propanol; 2-Methyl-1-(4-fluorophenyl)propan-2-ol; (4-Fluorophenyl)dimethylcarbinol
EINECS	220-882-5

Quality Control

Our production of 1-(4-Fluoro-Phenyl)-2-Methyl-Propan-2-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. Our quality system is designed to support cGMP and ISO 9001 standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.