Description

1-Methyl-1-Cyclohexanecarboxylic Acid Chloride is a versatile and highly reactive organic intermediate, primarily valued for its role as a key acylating agent in complex organic synthesis. Its structure makes it particularly useful for introducing the bulky 1-methylcyclohexanecarbonyl group into target molecules, a critical step in the development of advanced chemical entities. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that incorporate the cyclohexyl moiety for enhanced efficacy and stability.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers, including polyamides and polyesters, to alter physical properties.
• Organic Synthesis Reagent: Employed as a high-value acyl chloride reagent in academic and industrial R&D laboratories for peptide coupling, esterification, and amide bond formation.
• Dye and Pigment Manufacturing: Utilized in the synthesis of complex organic dyes and pigments where the introduction of a lipophilic cyclohexyl group is required.
• Flavor and Fragrance Ingredient: Functions as a precursor in the synthesis of certain musk fragrances and other aroma chemicals with specific olfactory profiles.

Basic Information

Product Name	1-Methyl-1-Cyclohexanecarboxylic Acid Chloride
CAS No.	2890-61-1
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	1-Methylcyclohexanecarbonyl Chloride; 1-Methylcyclohexane-1-carbonyl Chloride; α-Methylcyclohexanecarbonyl Chloride; NSC 403697; Cyclohexanecarboxylic acid, 1-methyl-, chloride; 1-Methylcyclohexylcarbonyl Chloride
EINECS	220-772-6

Quality Control

Our production of 1-Methyl-1-Cyclohexanecarboxylic Acid Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including assay by titration and impurity profiling by gas chromatography (GC), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts violently with water, strong bases, and alcohols. Containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain product integrity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%
Density (at 20°C)	1.04 - 1.08 g/mL
Refractive Index (n20D)	1.468 - 1.472

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.