Description

2-[1-[(3R,4S,5R)-3,4-Dihydroxy-5-(Phosphonooxymethyl)Oxolan-2-Yl]Imidazol-4-Yl]Acetic Acid is a high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 2888-19-9, is valued for its role as a key building block in the synthesis of complex nucleoside analogs and enzyme inhibitors. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and transferases.
• Proteomics & Molecular Biology: Employed in the development of chemical probes for studying cellular signaling pathways and protein function.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-[1-[(3R,4S,5R)-3,4-Dihydroxy-5-(Phosphonooxymethyl)Oxolan-2-Yl]Imidazol-4-Yl]Acetic Acid
CAS No.	2888-19-9
Molecular Formula	C10H15N2O9P
Molecular Weight	338.21 g/mol
Synonyms	1-(5-O-Phosphono-β-D-ribofuranosyl)imidazole-4-acetic Acid; Imidazoleacetic acid ribotide; 5'-Phosphoribosylimidazole-4-acetate; 4-(Carboxymethyl)-1-(5-O-phosphono-β-D-ribofuranosyl)imidazole; PRAI; 1-(5-Phospho-D-ribosyl)imidazole-4-acetic acid; 5'-Phosphoribosyl-4-carboxymethylimidazole; Imidazole glycerol phosphate synthase substrate analog
EINECS	Contact for details

Quality Control

Our 2-[1-[(3R,4S,5R)-3,4-Dihydroxy-5-(Phosphonooxymethyl)Oxolan-2-Yl]Imidazol-4-Yl]Acetic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.