Description

2',3',5'-Tri-o-Benzoyl-5-Iodouridine is a key protected nucleoside derivative, specifically a benzoylated and iodinated uridine analog. This compound is a critical synthetic intermediate in the production of modified nucleosides and oligonucleotides, enabling precise chemical transformations. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and advanced molecular probes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the preparation of modified oligonucleotides for research, diagnostics, and therapeutic applications.
• Biochemical Research: Serves as a precursor for labeled nucleosides used in mechanistic studies and probe development.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a protected, halogenated scaffold for further functionalization.
• Academic & Industrial R&D: Employed in laboratories for the discovery and development of new bioactive molecules targeting nucleic acid metabolism.

Basic Information

Product Name	2',3',5'-Tri-o-Benzoyl-5-Iodouridine
CAS No.	2880-91-3
Molecular Formula	C32H23IN2O9
Molecular Weight	730.34 g/mol
Synonyms	5-Iodo-2',3',5'-tri-O-benzoyluridine; 5-Iodouridine 2',3',5'-tribenzoate; 1-[(2R,3R,4R,5R)-3,4-Bis(benzoyloxy)-5-(benzoyloxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 5-Iodo-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)uracil; Tribenzoyl-5-iodouridine
EINECS	Contact for details

Quality Control

Our 2',3',5'-Tri-o-Benzoyl-5-Iodouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.