Description

5-Chlorouridine is a halogenated nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and a versatile intermediate for the synthesis of modified oligonucleotides and potential therapeutic agents. It is particularly valuable for researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug development, and molecular biology. The product is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Nucleic Acid Research: Used as a modified nucleoside in the synthesis of oligonucleotides to study RNA structure, function, and stability.
• Antiviral Drug Development: Serves as a key intermediate in the research and synthesis of nucleoside analog prodrugs targeting viral polymerases.
• Biochemical Probes: Incorporated into probes for studying cellular processes, enzyme mechanisms, and nucleic acid-protein interactions.
• Pharmaceutical Intermediates: A critical precursor in the multi-step synthesis of more complex active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Employed in laboratories for fundamental research in medicinal chemistry and chemical biology.

Basic Information

Product Name	5-Chlorouridine
CAS No.	2880-89-9
Molecular Formula	C9H11ClN2O6
Molecular Weight	278.65 g/mol
Synonyms	5-Chloro-1-β-D-ribofuranosyluracil; 5-Chloro-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; 5-Cl-Urd; 5-Chlorouridine, 1-β-D-Ribofuranoside; Uridine, 5-chloro-; 5-Chloro-1-(β-D-ribofuranosyl)uracil
EINECS	220-750-2

Quality Control

Our 5-Chlorouridine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality control includes identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.