Description

7-Deazainosine is a purine nucleoside analog characterized by a modified heterocyclic base structure, where a nitrogen atom in the imidazole ring is replaced by a carbon atom. This unique molecular architecture makes it a valuable intermediate and research chemical for the synthesis of novel nucleoside derivatives and analogs. It is primarily utilized in pharmaceutical research and development, particularly in the fields of antiviral and anticancer drug discovery. The compound is also of significant interest in biochemical studies investigating enzyme mechanisms and nucleic acid metabolism.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving purine nucleoside phosphorylases and other nucleoside-metabolizing enzymes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Nucleic Acid Chemistry: Employed in the preparation of modified oligonucleotides for probing biological processes or developing diagnostic tools.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	7-Deazainosine
CAS No.	2862-16-0
Molecular Formula	C11H13N4O5
Molecular Weight	281.24 g/mol
Synonyms	7-Carbainosine; 7-C-aza-Inosine; Tubercidin precursor; 7-Deaza-9-β-D-ribofuranosylhypoxanthine; 9-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol; 7H-Pyrrolo[2,3-d]pyrimidin-4-ol, 9-β-D-ribofuranosyl-
EINECS	220-684-8

Quality Control

Our 7-Deazainosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.