Description

3β,14-Dihydroxy-12-Oxo-5β-Card-20(22)-Enolide is a high-purity cardenolide derivative, a key structural motif found in biologically active natural products. This compound is of significant interest for its role as a critical intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis and study of novel therapeutic agents, particularly in cardiovascular and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the semi-synthesis of novel cardiotonic steroids and other bioactive molecules.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of related pharmaceutical compounds.
• Biochemical Research: Serves as a tool compound for studying the structure-activity relationships (SAR) of Na+/K+-ATPase inhibitors.
• Academic & R&D: Employed in university and institutional research for investigating natural product biosynthesis and medicinal chemistry.
• Preclinical Studies: Utilized in the early-stage development of potential therapeutic agents targeting specific cellular pathways.

Basic Information

Product Name	3β,14-Dihydroxy-12-Oxo-5β-Card-20(22)-Enolide
CAS No.	2842-85-5
Molecular Formula	C₂₃H₃₂O₅
Molecular Weight	388.50 g/mol
Synonyms	12-Oxocardenolide; 3β,14-Dihydroxy-12-oxo-5β-card-20(22)-enolide; 12-Oxo-3β,14-dihydroxy-5β-card-20(22)-enolide; 3β,14-Dihydroxy-12-oxocard-20(22)-enolide; 12-Oxodigitoxigenin; 3β,14-Dihydroxy-12-oxo-5β,14β-card-20(22)-enolide
EINECS	220-644-3

Quality Control

Our 3β,14-Dihydroxy-12-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.