Description

3-Tolyl Chlorothioformate is a versatile organosulfur reagent primarily used as a key building block in organic synthesis. Its value lies in its role as an acylating agent for the introduction of the tolylthioformyl group, enabling the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those containing thioester or thioamide functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the tolyl moiety imparts specific biological activity.
• Polymer Chemistry: Acts as a modifying agent or chain transfer agent in the development of specialty polymers with tailored properties.
• Chemical Research: Employed in academic and industrial R&D for method development and the construction of complex heterocyclic compounds.
• Ligand and Catalyst Preparation: Utilized for the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Tolyl Chlorothioformate
CAS No.	2812-83-1
Molecular Formula	C8H7ClOS
Molecular Weight	186.65 g/mol
Synonyms	m-Tolyl Chlorothioformate; 3-Methylphenyl Chlorothioformate; Chlorothioformic Acid O-(3-Methylphenyl) Ester; m-Tolyl Chlorothionoformate; 3-Methylphenyl Chlorothionoformate; Toluene-3-chlorothioformate; (3-Methylphenyl) Carbonochloridothioate
EINECS	220-571-6

Quality Control

Our 3-Tolyl Chlorothioformate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C or as specified on the label. Due to its nature as a strong acid/organic solvent and high volatility, keep away from heat, sparks, and open flame. Incompatible with strong bases, oxidizing agents, and moisture. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.