Description

D-A-Methyl Dopa is a specific enantiomer of the synthetic amino acid derivative, α-methyldopa. This compound is of significant interest in pharmaceutical research and development, particularly as a chiral intermediate or reference standard. It is primarily utilized by fine chemical manufacturers and research institutions engaged in the synthesis of specialized active pharmaceutical ingredients (APIs) and for analytical method development. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key chiral building block in the research-scale synthesis of specialized drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used as a high-purity standard in chromatographic methods (HPLC, GC) for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in enzymatic and metabolic pathway studies due to its structural similarity to natural dopa derivatives.
• Asymmetric Synthesis: Serves as a starting material or precursor in the development of novel asymmetric catalytic processes in organic chemistry.
• Pharmacology Studies: Utilized in preclinical research to investigate stereospecific biological activity and receptor interactions.

Basic Information

Product Name	D-A-Methyl Dopa
CAS No.	2799-15-7
Molecular Formula	C10H13NO4
Molecular Weight	211.22 g/mol
Synonyms	(R)-3-(3,4-Dihydroxyphenyl)-2-methylalanine; D-α-Methyldopa; (R)-α-Methyldopa; D-(-)-α-Methyl-3,4-dihydroxyphenylalanine; (2R)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid; MK-351; Lometon
EINECS	220-527-9

Quality Control

Our D-A-Methyl Dopa is manufactured and tested under a quality management system to ensure it meets the stringent requirements of research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identification data. We can supply material suitable for use as a reference standard, with specifications tailored to client needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.