Description

3-Hydroxy-5-β-Pregnan-20-One Hemisuccinate is a high-purity steroid derivative, specifically a hemisuccinate ester of a pregnane metabolite. This compound is a critical intermediate in the synthesis of specialized pharmaceutical agents and reference standards for analytical research. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of neurosteroids, hormone modulators, and diagnostic reagents. The product is supplied to meet the stringent quality requirements of advanced laboratory and cGMP production environments.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of neuroactive steroids and hormone analogs.
• Reference Standard: High-purity material for use in analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories.
• Biochemical Research: Used in studies investigating steroid metabolism, receptor binding, and the physiological role of pregnane derivatives.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of reagents for clinical assays and diagnostic kits.
• Metabolite Standard: Essential for the quantification of steroid metabolites in bioanalytical studies using techniques like LC-MS/MS.

Basic Information

Product Name	3-Hydroxy-5-β-Pregnan-20-One Hemisuccinate
CAS No.	2766-62-3
Molecular Formula	C25H38O6
Molecular Weight	434.57 g/mol
Synonyms	5β-Pregnan-3α-ol-20-one 3-hemisuccinate; 3α-Hydroxy-5β-pregnan-20-one hemisuccinate; Pregnanolone hemisuccinate; 5β-Pregnan-3α-ol-20-one hydrogen succinate; Allopregnanolone hemisuccinate (isomer); 3α-Hydroxy-5β-pregnan-20-one 3-hemisuccinate; 2766-62-3; Pregnane-3α,20-diol hydrogen succinate (derivative)
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-β-Pregnan-20-One Hemisuccinate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.