Description

4-Bromobenzyl Thiocyanate is a versatile organic building block featuring both bromo and thiocyanate functional groups on a benzyl scaffold. This dual functionality makes it a critical intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis. The compound, with CAS NO 2740-89-8, enables key transformations such as nucleophilic substitutions and cycloadditions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and potential drug candidates, particularly those requiring sulfur or bromine incorporation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the benzyl thiocyanate moiety is a valuable structural component.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and functional materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes that target specific biological pathways, leveraging the reactivity of the thiocyanate group.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.

Basic Information

Product Name	4-Bromobenzyl Thiocyanate
CAS No.	2740-89-8
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	1-(Bromomethyl)-4-thiocyanatobenzene; p-Bromobenzyl Thiocyanate; (4-Bromophenyl)methyl Thiocyanate; 4-Bromobenzyl Isothiocyanate (common misnomer); 4-Bromobenzyl Rhodanide; α-Thiocyanato-4-bromotoluene; NSC 401119; 4-Bromobenzylthio cyanate
EINECS	Contact for details

Quality Control

Our 4-Bromobenzyl Thiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.