Description

4-Cyanophenyl Isothiocyanate is a versatile bifunctional organic building block, combining a reactive isothiocyanate group with a cyano-substituted aromatic ring. This molecular structure makes it a critical intermediate for synthesizing advanced heterocyclic compounds and functional materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of thiourea derivatives and heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and high-performance resins.
• Chemical Biology & Proteomics: Acts as an affinity labeling reagent or a building block for bioconjugation probes due to the reactive isothiocyanate group.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic colorants and functional dyes.
• Ligand Synthesis for Catalysis: Used to prepare specialized ligands for metal complexes in catalytic applications.

Basic Information

Product Name	4-Cyanophenyl Isothiocyanate
CAS No.	2719-32-6
Molecular Formula	C8H4N2S
Molecular Weight	160.20 g/mol
Synonyms	p-Cyanophenyl isothiocyanate; 4-Isothiocyanatobenzonitrile; 1-Isothiocyanato-4-cyanobenzene; Benzonitrile, 4-isothiocyanato-; NSC 403119; (4-Isothiocyanatophenyl)carbonitrile; 4-CN-Ph-NCS
EINECS	220-324-7

Quality Control

Our 4-Cyanophenyl Isothiocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.