Description

1-Cyclobutene-1-Carbonyl Fluoride, 2-Methyl-4-(Trifluoromethyl)- (6Ci,8Ci) is a specialized fluorinated building block with a unique cyclobutene core structure. This compound is valued for its high reactivity, particularly as an acyl fluoride intermediate, enabling the efficient synthesis of complex molecules in advanced research and development. It is primarily sought by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring new fluorinated polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of specialty fluoropolymers with unique thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, especially in asymmetric synthesis.
• Fluorine Chemistry Research: An essential reagent for academic and industrial labs exploring new methodologies in fluorination and the construction of fluorinated heterocycles.
• Chemical Probe Synthesis: Used to create labeled compounds and probes for biochemical and diagnostic applications.

Basic Information

Product Name	1-Cyclobutene-1-Carbonyl Fluoride, 2-Methyl-4-(Trifluoromethyl)- (6Ci,8Ci)
CAS No.	2647-09-8
Molecular Formula	C7H6F4O
Molecular Weight	182.12 g/mol
Synonyms	2-Methyl-4-(trifluoromethyl)-1-cyclobutene-1-carbonyl fluoride; 2-Methyl-4-(trifluoromethyl)cyclobut-1-ene-1-carbonyl fluoride; 1-Cyclobutene-1-carbonyl fluoride, 2-methyl-4-(trifluoromethyl)-; 2647-09-8; 2-Methyl-4-trifluoromethyl-1-cyclobutene-1-carbonyl fluoride
EINECS	Contact for details

Quality Control

Our production of 1-Cyclobutene-1-Carbonyl Fluoride, 2-Methyl-4-(Trifluoromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for critical R&D and scale-up applications. Each lot is analyzed via GC, NMR, and IR spectroscopy to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture ingress and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.