Description

N6,N6-Dimethyladenosine is a chemically modified nucleoside derivative of adenosine, where two methyl groups are attached to the N6 position of the adenine base. This modification is critical for researchers studying RNA epigenetics, cellular signaling pathways, and the biochemical mechanisms of methylation. It serves as a valuable reference standard and building block for pharmaceutical and biotechnology applications. Key industries that utilize this compound include academic and industrial research institutions focused on molecular biology, medicinal chemistry, and the development of novel therapeutics.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of RNA modification, methylation processes, and epitranscriptomics.
• Pharmaceutical Intermediates: Serves as a key synthetic building block in the research and development of nucleoside-based antiviral or anticancer agents.
• Enzymology Studies: Employed as a specific inhibitor or substrate to investigate the activity and kinetics of methyltransferases and other nucleic acid-modifying enzymes.
• Diagnostic Development: Potential use in the formulation of assay kits and reagents for detecting specific RNA modifications.
• Life Science Reagents: Incorporated into specialized cell culture media or buffers for metabolic and signaling pathway analysis.

Basic Information

Product Name	N6,N6-Dimethyladenosine
CAS No.	2620-62-4
Molecular Formula	C12H17N5O4
Molecular Weight	295.30 g/mol
Synonyms	N6,N6-Dimethyladenosine; 6-(Dimethylamino)-9-β-D-ribofuranosyl-9H-purine; 6-(Dimethylamino)purine riboside; 6-Dimethylaminopurine riboside; 6-DMAPR; N6,N6-Dimethyl-9-β-D-ribofuranosyl-9H-purin-6-amine; Adenosine, N6,N6-dimethyl-
EINECS	220-076-6

Quality Control

Our N6,N6-Dimethyladenosine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support compliance with various research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.