Description

Diethyl Cyanomethylphosphonate is a versatile organophosphorus compound that serves as a critical building block in organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient synthesis of α,β-unsaturated nitriles. This makes it an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex molecule construction.

Application

• Key reagent in the Horner-Wadsworth-Emmons (HWE) olefination for synthesizing α,β-unsaturated nitriles (acrylonitriles).
• Building block for the synthesis of pharmaceutical intermediates, including potential active pharmaceutical ingredients (APIs).
• Precursor in the development of agrochemicals, such as herbicides and insecticides.
• Intermediate for the production of functionalized olefins used in material science and polymer chemistry.
• Reagent in the synthesis of natural products and complex organic molecules in research laboratories.
• Starting material for the preparation of phosphonate-based ligands and other specialty chemicals.

Basic Information

Product Name	Diethyl Cyanomethylphosphonate
CAS No.	2537-48-6
Molecular Formula	C6H12NO3P
Molecular Weight	177.14 g/mol
Synonyms	(Cyanomethyl)phosphonic Acid Diethyl Ester; Diethyl (Cyanomethyl)phosphonate; Diethyl Phosphonocyanidate; Cyanomethylphosphonic Acid Diethyl Ester; Diethyl Cyanomethanephosphonate; (Cyanomethylene)diethyl Phosphonate; NSC 169047; EINECS 219-795-9
EINECS	219-795-9

Quality Control

Our Diethyl Cyanomethylphosphonate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (by GC or HPLC) and impurity profiling, to ensure high chemical purity and consistency suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.