Description

4β-Hydroxy Cholesterol 4-Acetate is a high-purity sterol derivative, specifically an acetylated form of a hydroxylated cholesterol molecule. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily required by pharmaceutical R&D laboratories and biochemical manufacturers for the synthesis and analysis of steroid-based therapeutics and metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and reagent in studies of cholesterol metabolism, enzyme activity, and lipid biochemistry.
• Analytical Chemistry: Serves as a high-purity calibration standard for chromatographic (HPLC, GC) and spectroscopic analysis in quality control laboratories.
• Metabolite Synthesis: Employed in the preparation of specific cholesterol metabolites for biological testing and pathway elucidation.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and endocrinology.

Basic Information

Product Name	4β-Hydroxy Cholesterol 4-Acetate
CAS No.	2515-18-6
Molecular Formula	C₂₉H₄₈O₃
Molecular Weight	444.70 g/mol
Synonyms	4β-Hydroxycholesteryl Acetate; 4β-Hydroxycholest-5-en-3β-yl Acetate; Cholest-5-ene-3β,4β-diol, 3-acetate; 4β-Hydroxycholesterol Acetate; 4β-Hydroxycholesterol 3-Acetate; 4β-Acetoxycholesterol; 4β-Hydroxycholest-5-en-3β-ol Acetate
EINECS	Contact for details

Quality Control

Our 4β-Hydroxy Cholesterol 4-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling and spectroscopic identification (IR, NMR). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.