Description

3'-Amino-D-Adenosine is a modified nucleoside derivative where the 3'-hydroxyl group of the ribose sugar is substituted with an amino group. This structural modification makes it a valuable intermediate in the synthesis of novel oligonucleotides and nucleotide analogs for pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer therapeutics, and molecular probes. The compound's unique structure allows for targeted modifications in nucleic acid chemistry, enabling advanced studies in drug discovery and biochemical applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used in the study of enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Oligonucleotide Synthesis: Serves as a modified monomer for introducing amino-linked functional groups into DNA or RNA sequences.
• Probe Development: Facilitates the creation of labeled nucleotides for diagnostic assays and imaging studies.
• Antisense Technology: A potential component in the development of antisense oligonucleotides for gene silencing applications.
• Library Synthesis: Used in combinatorial chemistry to generate diverse libraries of nucleoside derivatives for screening.

Basic Information

Product Name	3'-Amino-D-Adenosine
CAS No.	2504-55-4
Molecular Formula	C10H14N6O3
Molecular Weight	266.26 g/mol
Synonyms	3'-Amino-2',3'-dideoxyadenosine; 3'-Aminoadenosine; 9-[(2R,3S)-3-Amino-2,3-dideoxy-β-D-erythro-pentofuranosyl]adenine; 3'-Amino-2',3'-ddA; D-3'-Aminoadenosine; Adenosine, 3'-amino-2',3'-dideoxy-, D-; 3'-Amino-2',3'-dideoxy-D-adenosine
EINECS	Contact for details

Quality Control

Our 3'-Amino-D-Adenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere or with desiccant to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.