Description

2'-Deoxy-5-Methylcytidine 5'-Monophosphate is a modified nucleoside monophosphate, a critical building block in nucleic acid chemistry and biochemistry. This compound is essential for research and development in areas requiring site-specific modification of DNA, particularly in the study of epigenetic markers like DNA methylation. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on oligonucleotide synthesis, molecular biology, and the development of novel therapeutics and diagnostic tools.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of modified DNA strands, enabling the incorporation of 5-methylcytosine residues at specific sites.
• Epigenetics Research: Used as a substrate or standard in studies investigating DNA methylation patterns, methyltransferase enzyme activity, and gene expression regulation.
• Antiviral/Anticancer Drug Development: Serves as a critical intermediate in the research and synthesis of nucleoside analog prodrugs targeting viral replication or aberrant cellular proliferation.
• Diagnostic Probe Manufacturing: Employed in the production of labeled probes and primers for techniques like PCR and sequencing that require sequence-specific methylation detection.
• Biochemical Reagent: Used in enzymatic assays and as a cofactor or inhibitor in studies of nucleotide-metabolizing enzymes.

Basic Information

Product Name	2'-Deoxy-5-Methylcytidine 5'-Monophosphate
CAS No.	2498-41-1
Molecular Formula	C10H16N3O7P
Molecular Weight	321.23 g/mol
Synonyms	5-Methyldeoxycytidine 5'-monophosphate; 5-Methyl-dCMP; 5-Methyl-2'-deoxycytidine 5'-phosphate; 5-Methyl-2'-deoxycytidylic acid; 2'-Deoxy-5-methylcytidylic acid; d5mCMP; 5-Methyldeoxycytidylic acid
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Methylcytidine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.