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3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-L-Galactopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 2446-63-1
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CAS No.:2446-63-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-L-Galactopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a specialized cardiac glycoside derivative, a compound class known for its potent biological activity. This high-purity reference standard is critical for ensuring analytical accuracy and consistency in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical manufacturers, and quality control laboratories engaged in the study or production of cardiac therapeutics and natural product chemistry.
Application
- Pharmaceutical Reference Standard: Serves as a primary or secondary standard for the quantitative and qualitative analysis (e.g., HPLC, LC-MS) of cardiac glycosides in drug substances and finished products.
- Biochemical Research: Used as a key reagent in studies investigating the mechanism of action, structure-activity relationships (SAR), and metabolism of cardenolides.
- Natural Product Isolation & Identification: Acts as a critical comparative standard for the isolation, purification, and structural elucidation of similar glycosides from plant extracts and biological matrices.
- Quality Control & Assurance: Essential for method development, validation, and routine QC testing in pharmaceutical manufacturing to ensure product potency, purity, and safety.
- Academic Research: Employed in university and institutional labs for pharmacological studies, including ion transport inhibition (Na+/K+-ATPase) and related cardiac effects.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-L-Galactopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide |
| CAS No. | 2446-63-1 |
| Molecular Formula | C35H54O14 |
| Molecular Weight | 698.80 g/mol |
| Synonyms | Gitoxin; Bigitalin; Anhydrogitalin; 16-Formylgitoxigenin 3-O-[4-O-(6-deoxy-α-L-galactopyranosyl)-β-D-glucopyranoside]; 3β-[(O-β-D-Glucopyranosyl-(1→4)-6-deoxy-α-L-galactopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; (3β,5β)-3-[(O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-α-L-galactopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Gitoxoside |
| EINECS | Contact for details |
Quality Control
Every batch of our 3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-L-Galactopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use as a high-grade reference material. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity (by HPLC), and impurity profiles to ensure compliance with your research or quality specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Related Substances (HPLC) | Total impurities ≤ 2.0%; Any single impurity ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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